Glutathione is a substance found in plants and animals as well as some bacteria and archaea. Its main role in the body is to prevent damage to important cellular components from free radicals and reactive oxygen species. These agents can include heavy metals and lipid peroxides.
Low levels of glutathione are associated with autoimmune diseases
In autoimmune diseases, glutathione levels are low due to damage to the immune system. This damage causes glutathione to be depleted, which causes more inflammation and destruction of tissue. Taking supplemental glutathione can help alleviate symptoms of these conditions, as it supports glutathione activity in the cells and helps maintain a healthy immune system. Glutathione also protects thyroid tissue from damage and inflammation. In healthy thyroid tissue, glutathione levels are high, but when the immune system is weakened, the body must lower its levels.
Cancer
Glutathione has a central role in the aetiology of cancer. It has been the focus of considerable attention for many years. It is the target of chemotherapeutic agents, but resistance to such agents has also been observed. Mutations, altered metabolism, and changes in the glutathione system can explain these resistances. More efficient inhibitors of glutathione are currently being developed, and these inhibitors may provide a useful basis for developing novel drug candidates.
Parkinson’s disease
Although there is a high degree of uncertainty surrounding the link between glutathione and Parkinson’s disease, the results of one recent study suggest that this antioxidant may be of some benefit. The study was conducted using tissue water as a reference to estimate the concentration of different metabolites.
Heart disease
A new study from the University of Utah suggests that the antioxidant, glutathione, may play a role in heart disease. The study, published in Cell, suggests that glutathione may help prevent and treat heart disease, as well as prevent and treat the symptoms of heart disease. The study has several potential implications, including the development of a new class of drugs for treating heart disease caused by “reductive stress.”
Psoriasis
Glutathione is an antioxidant found in the human body. It plays an important role in a number of different processes and can improve the immune system. It helps the body fight off toxins and inflammatory processes and can also help with many different autoimmune conditions, including psoriasis. The body naturally produces glutathione, but it can also be purchased through injections. Taking supplements of glutathione is an effective way to treat and prevent psoriasis.
Diabetes
Glutathione deficiency has been observed in patients with T2DM, especially those with microvascular complications. This deficiency is thought to be related to reduced synthesis and increased irreversible utilization of glutathione by non-glycemic mechanisms.